LaVerne L. Brown

Howard University
School of Pharmacy
2300 4th Street, NW
Washington, D.C. 20059
(202) 806-6452
Fax: (202) 806-4636

Dr. LaVerne L. Brown.
Assistant Professor
Department of Pharmaceutical Sciences.

Education

B.S. in Chemistry
Old Dominion University, Norfolk, VA.

Ph.D. in Organic/Natural Products Chemistry
Virginia Commonwealth University, Richmond, VA.

NIH Postdoctoral Fellow in Medicinal Chemistry
National Institute on Drug Abuse, Baltimore, MD.

Research Interests

Design and development of drugs for the treatment of neurological disorders and substance abuse.

Affiliations

American Chemical Society (Medicinal Chemistry Division).
American Association of Pharmaceutical Scientists (Drug Design and Discovery Section).
American Association of Colleges of Pharmacy.
Sigma Xi.

Publications

Book Review: GLENN D. CONSIDINE. Van Nostrand’s Encyclopedia of Chemistry, 5th edition. Hoboken, New Jersey: John Wiley & Sons; 2005. 1831pages, $195.00 (hardcover) ISBN: 0-471-61525-0. Reviewed By: LaVerne L. Brown, PhD, American Journal of Pharmaceutical Education 2005; 69 (4) Article 78.
“5-Substituted Derivatives of 6-Halogeno-3-((2-(S)-azetidinyl)methoxy)pyridine and 6-Halogeno-3-((2-(S)-pyrrolidinyl)methyoxy)pyridine with Low Picomolar Affinity for α4ß2 Nicotinic Acetylcholine Receptor and Wide Range of Lipophilicity: Potential Probes for Imaging with Positron Emission Tomography.” Zhang, Y.; Pavlova, O.; Chefer, S.; Hall, A.; Kurian, V.; Brown, L.; Kimes, A.; Mukhin, A.; Horti, A.; J. Med. Chem. 2004, 47, 2453-2465.
“Synthesis and Evaluation of a Novel Series of 5-(2-(4-pyridinyl)vinyl)-6-chloro-3-((1-methyl-2-(S)-pyrrolidinyl)methoxy)pyridine Analogues as Potential Positron Emission Tomography Imaging Agents for Nicotinic Acetylcholine Receptors”. LaVerne L. Brown, Santosh Kulkarni, Olga A. Pavlova, Andrei O. Koren, Alexey G. Mukhin, Amy H. Newman, and Andrew G. Horti, Journal of Medicinal Chemistry, 2002, 45, 2841.
“Radiosyntheses of 5-(2-(4-pyridinyl)vinyl)-6-chloro-3-(1-[11C]methyl-2-(S)- pyrrolidinylmethoxypyridine, a High Affinity Ligand for Studying Nicotinic Acetylcholine Receptors by Positron Emission Tomography”. LaVerne Brown, Olga Pavlova, Alexey Mukhim, Alane Kimes, and Andrew Horti, Bioorganic & Medicinal Chemistry, 2001, 9, 3055.